Spofford Lake is a 732-acre body of water in the town of Chesterfield in southwestern New Hampshire, United States. Water from Spofford Lake flows via Partridge Brook to the Connecticut River. In 2005 the New Hampshire Fish and Game Department named it the cleanest lake in southwestern New Hampshire, despite the amount of motor boating. …Spofford Lake is a 732-acre body of water in the town of Chesterfield in southwestern New Hampshire, United States. Water from Spofford Lake flows via Partridge Brook to the Connecticut River. In 2005 the New Hampshire Fish and Game Department named it the cleanest lake in southwestern New Hampshire, despite the amount of motor boating. The village of Spofford is located at the lake's outlet.